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Pandemic Pressure: How Azithromycin Use Shaped Resistance and Clonal Shifts in Staphylococcus aureusDuring the 2019 pandemic sweeping through hospitals, an insidious companion emerged in bloodstream infections, where bacteria ...
A study published in Frontiers explores the microbial diversity within hospital sink drains across multiple wards over a year-long period, focusing on bacterial communities, species identification, ...
More information: Eitan Yaffe et al, Brief antibiotic use drives human gut bacteria towards low-cost resistance, Nature (2025). DOI: 10.1038/s41586-025-08781-x ...
OptE is predicted to be a transmembrane effector protein that binds cyclic nucleotides. optSE potently restricted phage replication but mutant phages that had loss-of-function mutations in anti-CBASS ...
But bacteria are becoming increasingly resistant, and with a limited pipeline of new antibiotics, we risk effectively returning to the pre-antibiotic era where we can no longer treat infections.
The World Health Organization ranks antimicrobial resistance as one of the top 10 threats to global health. In 2019, bacterial antibiotic resistance killed an estimated 4.95 million people worldwide.
The authors present solid evidence linking cyclic di-GMP and the toxin HipH. The work is valuable because it establishes the relationship between bacterial persistence and biofilm resilience, which ...
The antimicrobial characteristics of the four NC-CRKP isolates, including the susceptibility profile, resistance genes, and porin-associated genes, were summarized in Table 2. Two of the Klebsiella ...
Bacteria engineered to destroy DNA can remove more than 99 per cent of genes that confer antibiotic resistance from wastewater. Treating wastewater with this method could help slow the spread of ...
In most cases, it is 10^-7 [one ten-millionth] colony-forming unit, or viable bacterial cell, per milliliter of broth. The resistance level should also be of a certain times higher — usually ...
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