How is antibody-drug conjugate (ADC) development impacting oncology? Key Takeaways Recent innovations across the multiple ADC components are critical to improving the therapeutic window as we advance ...

Conjugated polymers articles from across Nature Portfolio Conjugated polymers are organic macromolecules that are characterized by a backbone chain of alternating double- and single-bonds. Their ...

Results from a Phase Ia/Ib trial show that Eli Lilly’s LY4170156, an antibody drug conjugate (ADC) targeting folate receptor alpha (FRα), demonstrated notable anti-tumor activity in women with heavily ...

In-line optical phase conjugation is a well-known technique to enhance the received signal quality through nonlinearity compensation. Being able to implement the conjugation in cm-scale highly ...

Two high molecular weight conjugated polymers (CPs), i.e., poly [N,N′ -bis (4-tetradecyloctadecyl)-7,7′-difluoroisoindigo- alt -2,2′-bithiazole] (P2FI2Tz) and poly [N,N′ -bis (4-tetradecyloctadecyl)-5 ...

This paper aims to identify the current state of the art of the latest research related to Conjugate Gradient (CG) methods for unconstrained optimization through a systematic literature review ...

About Cynaptec Pharmaceuticals, Inc. - Cynaptec is a biopharmaceutical company dedicated to developing innovative therapies for neurological and psychiatric disorders. Cynaptec's initial development ...

Developing efficient adsorbents for uranium enrichment is of great significance for resource sustainability and environmental safety. This study presents a facile and adaptable post-synthetic strategy ...

The serum levels of conjugates of chenodeoxycholic acid (chenyl conjugates) and of cholic acid (cholyl conjugates) were determined by specific radioimmunoassays during a 24-hour period, which included ...