He then bred mice carrying the construct to mice expressing Cre recombinase in either excitatory neurons (Camk2a-Cre), inhibitory neurons (Gad2-Cre), astrocytes (mGfap-Cre), or microglia (Cx3cr1-Cre).

Using two-photon imaging in a transgenic mouse model of Alzheimer's disease, ... gfp inserted into Cx3cr1, transgenic APP Swe, tau P301L and yfp (Supplementary Methods and Supplementary Fig. 2).