The M280 variant gene differs from the usual CX3CR1 gene at two key points. Next, the NIAID researchers would like to discover if one, the other, or both of these changes cause the variant ...

The common CX3CR1 allelic variant was associated with increased GBM survival and with reduced tumor infiltration by microglia. The CX3CR1 polymorphism does not seem to be a risk factor for GBM but may ...

In conclusion, microarrays allowed us to identify CX3CR1 as a new candidate gene for asthma and our association study showed a potential susceptibility risk if carrying CX3CR1 common alleles of ...

Researchers found that certain types of immune cells called CX3CR1+ mononuclear phagocytes play a key role in innate and adaptive immune responses to intestinal fungi in mice. They also found that ...

A single amino acid substitution in the protein CX3CR1 may act as predictor for schizophrenia and autism, a multi-institute collaboration demonstrates.

In Crohn’s disease patients, a missense mutation in the gene encoding CX3CR1 was identified and found to be associated with impaired antifungal responses.

The team's findings suggest that patients who have the CX3CR1 gene variant might be misdiagnosed since they are negative for ASCA.

"By using mice that lack the Cx3cr1 gene that's expressed only in microglia in the brain," Gross tells Medical Xpress, "we were very sure to have only altered microglia, and that a deficit in ...

An inherited genetic variation of a protein that HIV can use to attach to cells, known as the CX3CR1 249I polymorphism, may partially explain long-term non-progression, according to Spanish ...

Researchers in Japan show in a multi-institute collaboration that a single amino acid substitution in the protein CX3CR1 may act as predictor for schizophrenia and autism.