When activated, cannabinoid receptors 1 and 2 tend to reduce pain and inflammation, while a third receptor, TRPV1, promotes the sensation of pain and contributes to inflammation.

Chemically modifying a synthetic cannabinoid could enable scientists to capitalize on the body’s natural pain-killing pathway without evoking drug tolerance or psychoactivity.

Testing a cannabinoid drug in disease models. The study explored the impact of WIN55.212-2, a synthetic compound targeting cannabinoid receptors, in rodent models mimicking early stages of ...

Cannabinoid receptors have two main types:: CB1 is found mostly in the neurological system, connective tissues, gonads, glands, and organs, while CB2 is found primarily in the immune system and ...

Cannabinoids are naturally occurring compounds found in the Cannabis sativa plant. Of over 480 different compounds present in the plant, only around 66 are termed cannabinoids. Skip to content ...

But overall, our findings suggest cannabinoids may acutely influence sleep, primarily by suppressing REM sleep, without ...

After testing the effect of the drug WIN55.212-2, which interacts with cannabinoid receptors, on rodents in the early stages of the disease, the team found "that they behaved in the same way as ...

While more research is necessary, some sources note that cannabinoid receptors may interfere with molecular pathways in the development of thyroid cancer, and could be potential therapeutic ...

This variation means there's less attraction between delta-8 and the cannabinoid receptor found on cells in your body. That's why a delta-8 high is less intense than the high you get from delta-9.

Research led by the University of the Basque Country (UPV/EHU) has identified a potential therapeutic pathway involving cannabinoid receptors to counter memory impairment in early stages of ...