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Cambridge Independent14h
Professor Sir Shankar Balasubramanian earns Royal Society of Chemistry’s Khorana Prize for quadruplex DNA research
Professor Sir Shankar Balasubramanian, from Cambridge, has won the Royal Society of Chemistry’s Khorana Prize in recognition ...
Split RNA switch system boosts precision of cell-specific gene expression control
Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...
Artificial nucleolus model reveals step-by-step process of ribosome assembly
Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But ...
C&EN5d
One-Electron Reduction Potential of the Neutral Guanyl Radical in the GC Base Pair of Duplex DNA | Journal of the American Chemical Society - ACS Publications
The one-electron oxidation of guanine in the GC base pair of DNA has been investigated using pulse radiolysis combined with DFT calculations. Reaction of benzotriazinyl radicals with DNA results in ...
C&EN6d
Hidden in Plain Sight: Subtle Effects of the 8-Oxoguanine Lesion on the Structure, Dynamics, and Thermodynamics of a 15-Base Pair Oligodeoxynucleotide Duplex - ACS Publications
The base lesion 8-oxoguanine is formed readily by oxidation of DNA, potentially leading to G → T transversion mutations. Despite the apparent similarity of 8-oxoguanine-cytosine base pairs to normal ...