Antibody-drug conjugates (ADCs) represent a mechanistically defined class of targeted therapeutics that combine monoclonal antibodies with cytotoxic payloads to achieve selective delivery to ...

The first patient in the trial has begun treatment with the novel, potential first-in-class B7-H3 directed antibody-drug conjugate (ADC). 1,2 “Patients with metastatic esophageal squamous cell ...

Third, Enhertu’s cysteine-based conjugation process is able to achieve a high drug-to-antibody ratio of around 7 to 8. This is much higher than the DAR’s of older generations of ADCs, which ...

The objective response rate across dose levels was 41.4%. A TROP2-directed antibody-drug conjugate, DB-1305/BNT325, demonstrated durable activity in patients with previously treated ovarian cancer ...

In this issue of The Lancet Oncology, another phase 2 trial conducted exclusively in China with a different HER2-targeted antibody–drug conjugate as the palliative second-line treatment of NSCLC is ...

Avenzo to receive exclusive global license (excluding Greater China) for development, manufacturing and commercialization of potential best-in-class EGFR/HER3 antibody-drug conjugate ...

Sanofi and SK Bioscience announced that they have entered a new collaboration to develop next-generation pneumococcal conjugate vaccines (PCVs) targeting both pediatric and adult populations.

There are four pneumococcal vaccines available. Different vaccines are recommended depending on age and medical status. The Food and Drug Administration (FDA) has licensed three pneumococcal conjugate ...

For most people, a pneumonia shot will last for life, and you’ll only need one shot. However, there are two different vaccines your doctor may recommend, and some people may need both. Here’s ...

tener conjugation imperfectConclusion Harnessing the power of tener conjugation imperfect unlocks a world of possibilities in Spanish communication. By understanding the principles, avoiding common ...