For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these ...

An international research team has deciphered a mechanism of the evolutionary arms race in human cells. The findings provide ...

Microglia replacement therapy helps treat people with a rare genetic condition called ALSP, suggesting the approach could ...

The discovery may explain why cutting edge CAR T-cell therapy has managed to revolutionized treatment for blood cancer but ...

Organ transplantation has significantly revolutionized the treatment of patients with organ failure. However, the recipient's immune system recognizes transplanted organs as foreign and elicits a ...

In this paper, the Shannon capacity of DNA data embedding is obtained for the case in which DNA sequences are subject to substitution mutations modeled using the Kimura model from molecular evolution ...

Tracking and characterizing mutations in a fast-evolving virus such as SARS-CoV-2, the cause of COVID-19, are valuable for an effective public health response and for developing treatments and ...

What is a missense mutation? A missense mutation occurs when there is a mistake in the DNA code and one of the DNA base pairs is changed, for example, A is swapped for C. This single change means that ...

The difference between hereditary (germline) and acquired (somatic) gene mutations in cancer can lead to much confusion. This is especially true if you’re hearing about genetic testing for a genetic ...

They found that a single mutation — called the Gln226Leu substitution — can "completely switch" the virus's preference, making it a match for humans instead of birds.