This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

Watson and Crick's discovery of DNA structure in 1953 revealed a possible mechanism for DNA replication. So why didn't Meselson and Stahl finally explain this mechanism until 1958?

This paper demonstrates that the mechanism of break-induced replication (BIR) is significantly different from S-phase replication, as it proceeds via a migrating bubble driven by Pif1 helicase ...

The first step in DNA replication requires the assembly of a group of proteins called the Origin Recognition Complex (ORC). Researchers have determined how the ORC assembles during the cell ...

Each replication bubble has two replication forks moving in opposite directions. As the replication bubbles progress along the DNA molecule, they eventually fuse, resulting in two complete and ...

The bubble-like mode of DNA replication can operate in non-dividing cells, which is the state of most of the body's cells, making this kind of replication a potential route for cancer formation.

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified.

DNA Replication Within the nucleus of every cell are long strings of DNA, the code that holds all the information needed to make and control every cell within a living organism.

DNA replication and replication stress In eukaryotes, DNA replication initiates at many replication origins that are distributed along the length of each chromosome arm. At each origin, two ...

DNA Day is held on April 25 to commemorate the publishing of the scientific papers that described the helical structure of the DNA molecule ...