If measured from beginning to end, the DNA in our cells is too long to fit into the cell's nucleus, explaining why it must be ...

Plant RNA viruses pose a significant threat to global agriculture, affecting a vast array of crop species and leading to ...

Whether antiretroviral therapy (ART) is always completely suppressive, or HIV might continue to replicate at low levels despite ART in some people with HIV (PWH), is still debated. Here, we ...

DNA leads to arrest in graduate student's 2004 murder after yearslong investigation Johnia Berry, 21, was stabbed more than 20 times in her Knoxville apartment.

But if you have a p53 mutation and you have dysregulated the G1-S cell cycle checkpoint, the cell is more likely to progress into S-phase with unrepaired DNA damage and have higher replication stress.

Some of these genes are also important in the DNA damage and repair (DDR) response and notably many other DDR genes, located in the wider genome, incorporated DNA regions that were enriched with ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

More information: Jason Alexander Halliwell et al, Sex-specific DNA-replication in the early mammalian embryo, Nature Communications (2024). DOI: 10.1038/s41467-024-50727-w ...

Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

Recent findings reveal that early mouse embryos replicate their DNA in a unique, uniform manner, which changes after the embryo grows beyond four cells. This early-stage replication is slower and more ...

The actual DNA replication occurs during the synthesis (S) phase, when two copies of the original cell DNA are produced, each containing one original and one new strand of DNA.