Cellular interactions between T cells and dendritic cells (DCs) in lymph nodes are crucial for the initiation of adaptive cell-mediated immunity. Two-photon imaging offers the opportunity to track ...

As part of the immune system, dendritic cells are essential for fighting body cells that have degenerated or are infected with a virus. They trigger an immune response by presenting protein ...

In eight tumors where patients failed immune checkpoint inhibitor (ICI) treatment, Plinabulin + radiation + PD-1 inhibitors demonstrated ...

Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus ...

Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus ...

In this article, we consider what dendritic cells (DCs) are, how they are generated, their function in the body and some medical conditions related to them. DCs are named for their distinctive ...

Researchers show how stimulating dendritic cells through certain pathways produces strong T cell activity against tumors and works in conjunction with immune checkpoint inhibitors to produce even ...

Dendritic cell activation and homing markers were also compared amongst these groups, generally showing similar dysregulation as previously reported, ...

Without Siglec-E, dendritic cells stayed hyperactivated, producing more pro-inflammatory cytokines like TNF-α and IL-6, and driving stronger T-cell responses against the allograft.

Beg and a team of researchers focused their investigation on two separate pathways that are known to contribute to activation of dendritic cells, the CD40 and the IFNβ pathways.They performed ...