The firm is launching a Phase II trial of its dendritic cell vaccine following promising preliminary efficacy and favorable safety results in Phase I.

In eight tumors where patients failed immune checkpoint inhibitor (ICI) treatment, Plinabulin + radiation + PD-1 inhibitors demonstrated ...

The pediatric tumor research group of the Cima Universidad de Navarra The combined strategy developed at Cima can overcome the limitations ...

Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus ...

Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus ...

Researchers from Instituto de Investigación Sanitaria Hospital Universitario de La Princesa and collaborators have developed nanoparticles loaded with poly(I:C) and used them to prime monocyte-derived ...

Figure 1. DC-mediated Anti-tumor Immune Response. DCs induce anti-tumor immune responses through a series of steps: Ag uptake, Ag processing, maturation, migration of DCs to the T cell regions of ...

Without Siglec-E, dendritic cells stayed hyperactivated, producing more pro-inflammatory cytokines like TNF-α and IL-6, and driving stronger T-cell responses against the allograft.

Clinical View on the Importance of Dendritic Cells in Asthma Rohit Gaurav; Devendra K Agrawal Disclosures Expert Rev Clin Immunol. 2013;9 (10):899-919.

Immune cells called regulatory T cells have long been known for their role in countering inflammation. In the setting of ...

Therefore, γδ T cells are essential for clearance of the parasites. Here, we found that γδ T cells play a key role in dendritic cell activation after Plasmodium infection. On day 5 postinfection, γδ T ...

Hypertension is associated with increased sympathetic outflow and subsequent activation of adaptive immunity. We hypothesized that renal sympathetic nerves activate dendritic cells, and that these in ...