Genetically engineered dendritic cells enhance the power of immunotherapy against lung cancer Novel treatment not only slowed down tumor growth in mice, but also activated the immune system to ...

Plasmacytoid dendritic cells can be activated with viral and bacterial DNA via TLR9. Activated pDCs promote generation of both Th1/Th17 cells [46,76,87,92] and Tregs [104,105].

Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus ...

Researchers use $2.4 million grant for dendritic cell cancer immunotherapy; will study hybrid drug delivery vehicle that breaks through intracellular traffic jams.

In an innovative new study of glioblastoma, scientists used artificial intelligence (AI) to reprogram cancer cells, converting them into dendritic cells (DCs), which can identify cancer cells and ...

Learning Objectives: 1. Identify the key roles of dendritic cells in cancer immunotherapy, including their use as antigen-loaded vaccines and intratumoral adjuvants. 2. Explain the strategies used to ...

In recent decades, immunotherapy has transformed cancer treatment, offering effective options for diseases once considered uncurable, such as melanoma, lung, and bladder cancers. What began as ...

Studies presented at the ASCO Annual Meeting 2025 highlighted immunotherapies that may provide new standards of care for certain cancers as well as immunotherapies that are breaking new ground by ...

Adoptive immunotherapy via transfer of type I dendritic cells (cDC1s) is a more effective against tumors treatment than transfer of type II dendritic cells (cDC2s).

The Th-1 dendritic cell immunotherapy is currently being investigated in the phase 1 DECIST trial.

Genetically engineered dendritic cells enhance the power of immunotherapy against lung cancer by Denise Heady, University of California, Los Angeles ...

This article reviews select aspects of plasmacytoid dendritic cell biology -- relevant to the disease pathogenesis and immunotherapy in multiple sclerosis.