Introduction Human liver glycerol-3-phosphate dehydrogenase (hl GPDH) is a dimeric enzyme that catalyzes the NADH-dependent reduction of cytosolic dihydroxyacetone phosphate (DHAP) to ...

3-Hexulose-6-phosphate synthase, a key enzyme in the ribulose monophosphate pathway, plays a central role in formaldehyde assimilation and detoxification, offering great potential for third-generation ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...