The triplication of a region of chromosome 21 around D21S55 in 21q22.2–22.3 has been involved in the main features of Down syndrome including mental retardation (Down syndrome chromosome region ...

Trisomy is a genetic condition characterized by the presence of an extra chromosome. This means that the affected person has ...

To determine which regions of chromosome 21 are involved in the pathogenesis of specific features of Down syndrome, we analysed, phenotypically and molecularly, 10 patients with partial trisomy 21.

Scientists in Japan have used gene-editing technology to remove the extra chromosome responsible for Down syndrome, at least ...

Scientists map second human chromosome. By Ann Schrader Denver Post Science Writer. May 9 - Scientists in Denver, Japan and Germany have mapped chromosome 21, a feat that could one day lead to ...

Using genetic mapping, the researchers identified a gene on human chromosome 21 called Dyrk1a, which causes heart defects when present in three copies in the mouse model of Down syndrome.

To more precisely understand the impact of the extra chromosome 21, ... The study 'Single-cell multi-omics map of human fetal blood in Down syndrome' has been published in Nature. RELATED TOPICS.

People with Down syndrome have an extra chromosome that impacts their looks and their ability to think, learn, and reason. Discover the type, causes, and kinds of effects it can have.

They sifted through published datasets of proteins and RNA from individuals with Down syndrome and compared these to laboratory-made cells with trisomies of chromosomes 3, 5, 12, and 21.The ...

The presence of extra genetic material found among persons with Down syndrome may lead to abnormalities in the immune system and a higher susceptibility to certain illnesses, such as Alzheimer's ...

The guest is Julie Torzewski, executive director of Down Syndrome of Louisville. An expecting mother is told that her baby has trisomy 21 but doesn't understand exactly what that means. Dr ...