More information: Jennifer C. Earp et al, Structural basis of siderophore export and drug efflux by Mycobacterium tuberculosis, Nature Communications (2025). DOI: 10.1038/s41467-025-56888-6 ...

Finding a way to disable the efflux transporters of M. tuberculosis with an inhibitor would strike a double blow — restore microbial sensitivity to antibiotic bedaquiline and break the cycle that ...

New Technologies Numerous ductless heat pump systems are now available for cold climates. These include most of Fujitsu’s AIRSTAGE H and J-Series ductless products, which meet — and often exceed — the ...

Gautam Kumar, Priya Mondal and Amit Kadam et al. Combating Multi-drug Resistant Mycobacterium Species by Efflux Pump Inhibitors: Contemporary Trends. BIOI. 2025. Vol. 6 (1). DOI: ...

An efflux pump is a mechanism used by bacteria to actively transport antibiotics out of the cell, reducing the drugs’ effectiveness. The role of the MAB_2302-MAB_2303 gene pair as a direct efflux pump ...

New Yorkers might finally be able to go hands-free at the gas pump if one upstate lawmaker gets his way. State Sen. Joe Griffo (R-Onedia) has introduced a bill to greenlight the use of clips to ...

But since each vector is a high-dimensional float array, performing brute-force similarity comparisons across a large dataset can become prohibitively expensive, which is where vector indexing comes ...

Keeping up with today’s commercial HVAC trends helps HVAC business owners and technicians thrive in an evolving industry. Staying on top of advancements and changes, whether innovative all-climate ...

Noctua's thermosiphon system doesn't use a pump to push the coolant around the loop. Instead, it relies on a liquid undergoing a phase change (i.e., turning into a vapour) at the CPU, which rises ...

As for the Devens site where BMS plans to relocate viral vector production, the 700,000-square-foot plant handles both process development and commercial manufacturing. The FDA cleared a facility ...

Adebusayi et al. found that efflux pumps in P. fluorescens had higher output at a cultivation temperature of 10ºC compared to 28ºC or 35ºC. 15 However, Martins et al. conclude that Salmonella spp., ...

Abstract The model multi-drug efflux pump from Escherichia coli, EmrE, can perform multiple types of transport leading to different biological outcomes, conferring resistance to some drug substrates ...