Using this method, the researchers could monitor the fluctuations of SOX2 and OCT4 over time in living cells and determine how these fluctuations impact the fate of the embryonic stem cells.

Scientists have identified about two dozen genes that control embryonic stem cell fate. The genes may either prod or restrain stem cells from drifting into a kind of limbo, they suspect. The limbo ...

But it also allowed people to ask what makes an embryonic stem cell distinct. Over time, scientists created a list of a few dozen genes that were consistently active in stem cells of various types.

miR-34a-deficient embryonic stem cell culture is enriched with cells with expanded developmental potential as shown by their strong MuERV-L induction (red).

Pluripotent embryonic stem cells (ESC) are valuable tools for understanding developmental processes and have tremendous clinical potential if their lineage commitment can be tightly controlled.

A pioneering new study led by Florida State University biologists could fundamentally change our understanding of how embryonic stem cells differentiate into specific cell types. The research, ...

Every stem cell faces a decision to become a mature epidermal cell or switch to becoming a hair follicle cell. This so-called fate switch is governed by the transcription factor SOX9.

Chang, Dr. Eran Segal from the Weizmann Institute in Israel and their colleagues constructed a gene module map to systematically relate transcriptional programs in embryonic stem cells (ESCs ...

Their collaboration has resulted in engineered cells called ‘synthetic organizers’ that deliver instructions to stem cells, telling them to grow into specific tissues and organs.

Scientists have identified about two dozen genes that control embryonic stem cell fate. The genes may either prod or restrain stem cells from drifting into a kind of limbo, they suspect. The limbo ...

Scientists have identified about two dozen genes that control embryonic stem cell fate. The genes may either prod or restrain stem cells from drifting into a kind of limbo, they suspect. The limbo ...

UCSF scientists have identified about two dozen genes that control embryonic stem cell fate. The genes may either prod or restrain stem cells from drifting into a kind of limbo, they suspect. The ...