During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo.

Vepdegestrant is an oral proteolysis-targeting chimera (PROTAC) estrogen receptor (ER) degrader that directly harnesses the ubiquitin–proteasome system.In this phase 3, open-label, randomized ...

Background: Prostate cancer relies on the androgen receptor (AR) pathway as a key oncogenic driver. BMS-986365 is a heterobifunctional, orally bioavailable ligand-directed degrader targeting the AR ...

Rediscovering the first known cellular receptor Study applies new techniques to reexamine a receptor linked to sepsis and resolve contradictions regarding its binding interactions with other ...

Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors plus endocrine therapy (ET) represents the standard first-line treatment for patients with hormone receptor–positive/human epidermal growth factor ...

President Trump has championed access to in vitro fertilization (IVF) and even dubbed himself the “fertilization president” early in his second term. But Department of… ...

During a White House speech for Women’s History Month, President Donald Trump dubbed himself the "fertilization president" while touting his efforts to expand access to in vitro fertilization.

Nevada Senate Democrats introduced a bill Wednesday to protect and expand access to in vitro fertilization treatments. Senate Bill 217, sponsored by Senate Majority Leader Nicole Cannizzaro and ...

Better receptor binding doesn’t necessarily cause disease on its own. Several other factors are important, such as the virus’s ability to replicate and proliferate in the body.

ApoE3 and ApoE4 ferry lipids into cells via lipoprotein receptor. Weak receptor binding prevents ApoE2 and Christchurch variants from doing the same. Peroxidation-prone lipids borne by ApoE3/4 cause ...

IVF is a decades-old procedure that has allowed increasing numbers of prospective parents to have children. Evolving legislation may put it under threat.

“The metaphors we use in discussing biological processes like fertilization are powerful: They both reflect and produce collective understandings of our bodies, ourselves, and our society,” said ...