B7-33 is a synthetic peptide derived from the relaxin protein family, specifically designed to interact with the relaxin ...

Scientists have developed a technique that aligns stem cells into a single sheet, resulting in a marked increase in the secretion of signaling proteins which help repair tissue and regulate the immune ...

Preclinical study results provide a comprehensive transcriptomic characterization of regenerative wound repair in the oral mucosa.

The delicate balance between cell death and regeneration is crucial for human health and longevity. Most mechanisms involved ...

Scientists have found a novel way that includes a new lab-grown material that could help slow and even reverse some of the ...

Background Idiopathic pulmonary fibrosis (IPF) is characterised by damage to the epithelial layer, closely associated with the alveolar basement membrane (BM). We aimed to investigate how type IV ...

Researchers at Baylor College of Medicine and collaborating institutions have uncovered a key molecular player that is involved in lung repair and in the development of pulmonary fibrosis, a common ...

Liver fibrosis is the build up of scar tissue in the liver when it tries to heal itself. Symptoms may include fatigue, swelling, and weight loss.

Tissue samples collected at various time points were analyzed for fibrosis-related gene expression changes and collagen content. Low (1.5 U/kg) and high-dose (2.5 U/kg) bleomycin instillations alone ...

4 The roles of tissue Tregs in tissue repair and fibrosis In this section, we discussed the specific roles of tissue Tregs in tissue repair and fibrosis across various pathological contexts, focusing ...

So, TREM2 in liver macrophages is critical for promoting tissue repair and preventing excessive fibrosis, suggesting its potential as a therapeutic target.