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Many doubted the GFP gene would produce the glowing protein on its own. But when Chalfie put it in bacteria and shined a blue light on them, they glowed. Chalfie's 1994 paper on the gene ...
GFP has been recognized as a marker in intact cells for gene expression and protein targeting. In biological studies, it is extensively used as genetically encoded fluorescent markers.
But first, the gene that creates the GFP protein needed to be found. William Ward, a professor at Rutgers University, met Douglas Prasher on a jellyfish-hunting expedition in the 1980s.
A green fluorescent protein makes fruit fly sperm glow green. (Image credit: Catherine Fernandez and Jerry Coyne.) GFP remains special, however, because it spontaneously folds into the right shape ...
Researchers have developed a new gene-editing platform that will enable safer and more effective T cell–based immunotherapies ...
A transgenic line of monkeys carrying a gene encoding green fluorescent protein fully integrated into their DNA has been created for the first time. The research, published in the journal Nature ...
Since Prasher cut the GFP gene out of the jellyfish genome with restriction digestion enzymes, the clone had extra DNA segments that bookended the GFP gene. If Chalfie and Euskirchen wanted only the ...
Fluorescence images showing targeted green fluorescent protein (GFP) gene expression in cones. Refer to Table 1 for specific details. (a–c) 3LCR-PR0.5-GFP (dog M571, left eye, ...
In this system, base-editing activity results in the expression of green fluorescent protein (GFP). The team installed a mutation in the bacterium's GFP gene to remove its fluorescence.
Fluorescent jellyfish gene sheds light on 'fitness landscape' Date: May 12, 2016 Source: Centre for Genomic Regulation Summary: By studying more than 50,000 variants of a jellyfish gene ...
Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse ...