To study the mutually exclusive expression of odorant receptor (OR) genes, we generated transgenic mice that carried the murine OR gene MOR28. Expression of the transgene and the endogenous MOR28 ...

The study provides a potential framework for dissecting mechanisms underpinning the failure of regeneration in other organs ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

XPro™ treatment post-TBI shows promise in reducing Alzheimer’s-like pathology in transgenic mice, improving neurological outcomes. Quiver AI Summary INmune Bio, Inc. announced promising ...

University of Texas Southwestern Medical Center scientists found that activating fibroblast growth factor 21 (FGF21) ...

Studies in human cell lines and transgenic mouse models show that non-receptor tyrosine-protein kinase TYK2 phosphorylates tau at Tyr29 and thereby promotes its stabilization and accumulation.

Cas13d-treated mice had significantly lower intraocular pressure than untreated control mice in both wild-type and glaucoma mouse models. The gene editing treatment does not permanently change the ...

The bacteriophage P1 Cre/ lox P system has become a powerful tool for in vivo manipulation of the genomes of transgenic mice. Although in vitro studies have shown that Cre can catalyze recombination ...