Arialys Therapeutics' precision medicine has shown preclinical potential to address the underlying cause of anti-NMDA receptor encephalitis (ANRE), a rare brain disorder that comes with severe ...

Enhanced ADCC (antibody-dependent cellular cytotoxicity): The engineered dimeric IgG1 backbone not only delivers payload but actively engages the immune system to kill tumor cells directly.

Without treatment, one-third of people living with CIDP will need a wheelchair. About Efgartigimod SC Efgartigimod SC (efgartigimod alfa) is a human IgG1 antibody fragment designed to reduce ...

These forward-looking statements can be identified by the use of forward-looking terminology, including the terms "aim,” "is,” "can,” "may,” "will,” and "believe” and include statements argenx makes ...

VYVGART® SC, first-and-only IgG Fc-antibody fragment which specifically targets the neonatal Fc receptor (FcRn), now approved for use in Europe for CIDPApproval based on ADHERE clinical trial ...

Research Highlight Published: August 2003 Antiviral immunity Antibodies lock arms against HIV Jennifer Bell Nature Reviews Immunology 3, 604 (2003) Cite this article ...

Affinity chromatography remains one of the main methods for purifying antibodies, enabling high specificity and yield. Whether working with recombinant monoclonal antibodies or polyclonal antibodies ...

ART5803 is a humanized, monovalent IgG1 antibody engineered to selectively bind the GluN1 subunit of the NMDA receptor without disrupting receptor function or causing internalization.

Both 6B2 tau antibody and IgG1 were also taken up in a time-dependent manner (Figures 6A, 7A), and distinctly localized in the neurites and more distal processes of the DC, with limited visibility in ...

Results Prominent reactivity against a 56 kDa protein was detected in human H69 cholangiocyte lysates exposed to sera of nine patients with IAC/AIP. Affinity purification and mass spectrometry ...

Antibody-drug conjugates (ADCs) represent a mechanistically defined class of targeted therapeutics that combine monoclonal antibodies with cytotoxic payloads to achieve selective delivery to ...