As Synedgen's Chief Executive Officer and Chief Scientific Officer, Dr. Saward will continue to lead the company to deliver on the successful partnership with Biomedical Advanced Research Agency (BARD ...

The study looked at a drug called spironolactone. It’s normally used to treat high blood pressure, but it’s now showing ...

In people with diabetes, this layer is often damaged, which leads to kidney problems over time. Spironolactone seems to protect the glycocalyx from harm, helping the kidneys function better for ...

Heparan sulfate glycosaminoglycans in the stem cell glycocalyx are crucial in controlling growth factor activity during development. Augmenting the surface of stem cells with synthetic heparan sulfate ...

These effects are primarily mediated by mechanosignal transduction through focal adhesions, glycocalyx, cell-cell junctions, ion channels, and Notch receptors. Such mechanical signaling can upregulate ...

The glycocalyx is a carbohydrate-rich layer that lines the endothelial surface, providing a protective barrier against mechanical forces and maintaining vascular homeostasis. 16 The flushing catheter ...