By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered ...

At MIT, one genome researcher is testing a different approach. Bin Zhang, associate professor of chemistry and the leader of ...

In the earliest hours after fertilization, an embryo takes its first steps toward becoming a living organism by shedding ...

Life depends on genes being switched on and off at exactly the right time. Even the simplest living organisms do this, but usually over short distances across the DNA sequence, with the on/off switch ...

Despite rapid advances in genome and exome sequencing, many individuals with rare diseases remain undiagnosed. In a ...

Increased vegetation growth in European mountains, driven by climate and land-use changes, reduces the genetic diversity of ...

Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. While scientists believe that gut microbiota play an ...

The new perspective involves a basic dichotomy: The human genome is about six feet long when the DNA is stretched end to end, but it must fit into the nucleus of a cell, which is 80 times smaller than ...

Our results establish a role for METTL3 and 6mA in promoting genome stability in mammalian cells, especially in response to base damage. In this study, we provide evidence that 6mA is greatly enriched ...