This important study fills an gap in our knowledge of the evolution of GPCRs in holozoans, as well as the phylogeny of associated signaling pathway components such as G proteins, GRKs, and RIC8 ...

Billions of years ago, a rock crack exuding heat could have brought different biomolecules together to kickstart protein ...

How to use computational methods to effectively predict the function of proteins remains a challenge. Most prediction methods based on single species or single data source have some limitations: the ...

LMU researchers have demonstrated a possible mechanism for metabolic processes without cell membranes in water-filled pores.

Looking at life today, it is difficult to imagine how complex biological processes and structures could have developed from ...

Most of us turn to coffee for a quick boost in the morning—but new research suggests that caffeine may also be helping our ...

Caffeine appears to affect how cells handle stress and DNA damage—but researchers say it’s no magic bullet. Here’s what the ...

Scientists have long used fluorescent dyes—which emit light—to research cell structures and activities. By attaching ...

It has been over 60 years since Osamu Shimomura et al. discovered Green Fluorescent Protein (GFP)1. Since then, the color ...

Researchers at the Max Planck Institute for Molecular Genetics have developed a novel synthetic micropeptide termed the "killswitch" to selectively immobilize proteins within cellular condensates, ...

Fluorescent proteins from the green fluorescent protein (GFP) family interact strongly with CdSe/ZnS quantum dots. Photoluminescence of GFP5 is suppressed by red-emitting CdSe/ZnS quantum dots with ...

Accurate identification of protein-protein interaction (PPI) sites is crucial for understanding the mechanisms of biological processes, developing PPI networks, and detecting protein functions.