AstraZeneca and Moderna both used the HEK293T cell line in early studies on their vaccines. Johnson & Johnson used a different cell line called PER.C6 , also derived from fetal cells, to test its ...

It is “based on extracts from HEK293T cells that are engineered to endogenously express GADD34 and K3L proteins, which suppress phosphorylation of translation initiation factor elF2α,” they ...