Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the "macrodomain," found in all coronaviruses such as SARS-CoV-2 and ...

Researchers reveal how hydration shapes peptide assembly on 2D materials, offering new insights for bioelectronics and ...

Kanazawa University, report in Small, on how short peptides self-assemble linearly on atomically-thick solid surfaces, such ...

The researchers designed short and simple dipeptides, mainly consisting of alternating amino acids with aromatic side groups, tyrosine (Y) and histidine (H) (Fig. 2). The former is hydrophobic residue ...

Each amino acid is assigned a value reflecting its tendency to be found in hydrophobic (water-avoiding) or hydrophilic (water-attracting) environments. Despite certain limitations, the Kyte–Doolittle ...

The potentials of mean force of 21 heterodimers of the molecules modeling hydrophobic amino acid side chains: ethane (for alanine), propane (for proline), isobutane (for valine), isopentane (for ...