Our objectives were to ascertain the importance of BAFF and APRIL in the inflammatory processes associated with SLE via transcriptional datasets and in vitro assays, and to evaluate the efficacy of ...

Instead of extracting T-cells and engineering them in a lab, researchers have delivered mRNA directly into circulating immune ...

In response to growing market demand for tools that address these concerns, CN Bio has expanded the in vitro to in vivo extrapolation (IVIVE) capabilities of its established PhysioMimix ® DILI assay, ...

Once thought improbable, in vitro human models are demonstrating technological prowess in a growing range of applications.

WASHINGTON — A model predicting the development of systemic lupus erythematosus, based on genetic, lifestyle and environmental factors, was successfully validated in a large cohort, according to ...

In a new case report, investigators recommend that in women with systemic lupus erythematosus (SLE), physicians must work closely with the woman to determine whether in vitro fertilization (IVF, a ...

Preclinical in vitro model of monocyte influence on microvessel structure in systemic lupus erythematosus Author affiliations • Holly Ryan 1 , Alison Veintimilla 2 3 , Christine Groso 1 , Erika Moore ...

Systemic lupus erythematosus (SLE) is a severe multisystem autoimmune disease that can cause injury in almost every body system. While considered a classic example of autoimmunity, it is still ...