Three-dimensional (3D) cancer models have emerged as pivotal tools in oncology research, offering a more accurate representation of tumor biology compared ...

Antiphospholipid antibodies in an in vivo thrombosis model in mice. Lupus.1994; 3:247–251. Crossref Medline Google Scholar 39 Del Papa N, Guidali L, Sala A, Buccellati C, Khamashta MA, Ichikawa K, ...

Background Abnormalities of type I interferon signaling and production can initiate lupus development. Disturbances of nucleic acid-sensing molecules triggered autoreactivity in lupus mouse models.

The trial will evaluate efficacy, safety and tolerability of two regimens of ianalumab compared to placebo, given as monthly or quarterly subcutaneous (s.c.) injection on top of standard-of-care (SoC) ...

On June 24, the company announced receipt of FDA approval for a 200 mg/mL autoinjector of Benlysta (belimumab) for the treatment of active lupus nephritis (LN).

Hydroxychloroquine is tied to reduced preeclampsia risk but not preterm birth risk in pregnant patients with lupus in a Swedish cohort study.

The Michael Jon Barlin Pediatric Lupus Research program provides funding for research projects that have the potential to significantly advance the field of or impact the lives of children living with ...

BOSTON, June 25, 2025 /PRNewswire/ -- The Lupus Research Alliance (LRA) proudly awarded the 2025 Lupus Insight Prize today to highly respected immunologist Deepak Rao, MD, PhD, Brigham and Women's ...

Our objectives were to ascertain the importance of BAFF and APRIL in the inflammatory processes associated with SLE via transcriptional datasets and in vitro assays, and to evaluate the efficacy of ...

Instead of extracting T-cells and engineering them in a lab, researchers have delivered mRNA directly into circulating immune ...

Although lupus-related medical complications affect pregnancy outcomes, social determinants and economic conditions, known as social determinants of health (SDOH), may also be important in shaping ...