When the insulin nanoparticle enters an acidic environment of the stomach, its layers start to repel each other, resulting in the slow release of insulin from the outermost layer, ...

Bae and his colleagues found nanoparticle size matters. They fed rodents oral nanoparticles in two sizes (100 or 250 nm) at doses ranging from 1 to 20 mg/kg. Surprisingly, larger nanoparticles were ...

Up to 3% of people with diabetes have an allergic reaction to insulin. A team at Forschungszentrum Jülich has now studied a method that could be used to deliver the active substance into the body ...

Long-acting insulin might also be used to provide a slow, steady release of insulin. The use of nanoparticles to deliver drug and gene therapy has had a tremendous impact on how diseases are treated.

NTU Singapore scientists have developed insulin nanoparticles that may become an alternative to insulin injections for diabetics. Delivering insulin orally would be preferable over insulin jabs ...

After testing several sizes of nanoparticles, Whitehead and coworkers found that ones smaller than 100 nm improved insulin’s passage through mouse intestines.

Plus, the nanoparticles themselves have a high capacity for insulin, of around 65 weight-percent. Of course, further work will be needed to investigate whether the benefits carry across to humans.

Producing dry insulin nanoparticles through spray drying may open the door to dosage forms such as oral tablets or bioadhesive films, according to research published in the Nature journal ...

"In this experiment, we exposed mice to a weak electromagnetic field (1 kHz, 21 mT) for just three minutes each day," said Fussenegger. "This controlled their insulin secretion really well and ...

The nanoparticles are composed of multiferric cores (Cobalt ferrite and Bismuth ferrite which responsive to magnetic field) and chitosan outer layers ... like insulin, to life." ...