Among the striking findings: The atlas’ molecular view of kidney function reveals spatially specific lipid biomarkers for distinct functional tissue units of the nephron.

The kidney, a critical organ for waste filtration and fluid regulation, is the subject of a groundbreaking molecular mapping project that could reshape our understanding of renal health. Despite ...

Chronic kidney disease (CKD) is a global health threat, affecting over 10% of the world population, including an estimated 37 million Americans. Importantly, glomerular diseases account for 70% of all ...

The human kidney is a masterclass in biological engineering. Responsible for filtering approximately 50 gallons of blood ...

Our results support the scientific premise and physiological relevance that NHE3 in the proximal tubules plays an essential role in maintaining basal blood pressure homeostasis, and genetic deletion ...

In this study, we propose V-SAM, a novel architecture designed to overcome these limitations and enhance segmentation performance in the medical domain, specifically for glomerulus segmentation in ...

Total kidney histology scores include assessments of glomerular, tubular, and interstitial lesions. Data from individual mice are plotted, with horizontal and vertical bars representing median and ...

In addition, in the fly Malpighian tubule, the Drosophila renal tubule that is similar to the mammalian nephron tubule, dysbiosis also activates the NFκB/Imd pathway and disrupts metabolic homeostasis ...

With tumor progression metabolism of the body is disturbed and toxic metabolites, entering the blood, can affect the structure of organs distant from tumor growth. The kidneys are one of the main ...