The human kidney is a masterclass in biological engineering. Responsible for filtering approximately 50 gallons of blood ...

This review presents a concise update of nongenomic effects of aldosterone on the mammalian renal tubule. Emphasis is placed on ion transport proteins regulated by aldosterone through nongenomic ...

Chronic kidney disease (CKD) is a global health threat, affecting over 10% of the world population, including an estimated 37 million Americans. Importantly, glomerular diseases account for 70% of all ...

In addition, in the fly Malpighian tubule, the Drosophila renal tubule that is similar to the mammalian nephron tubule, dysbiosis also activates the NFκB/Imd pathway and disrupts metabolic homeostasis ...

Objective BAFF and APRIL signal through TACI, BCMA, and/or BAFF-R, and play important roles in the activation, differentiation, and/or survival of B cells, particularly antibody-secreting cells, as ...

With tumor progression metabolism of the body is disturbed and toxic metabolites, entering the blood, can affect the structure of organs distant from tumor growth. The kidneys are one of the main ...

Segmenting FTU in kidney images presents a unique challenge due to the small size and complex shape of the glomerulus. The kidney's anatomical complexity makes it difficult for conventional ...

The effects of treatment on survival, proteinuria, kidney histology, glomerular IgG deposition, cytokine-secreting cells, and circulating cytokines were measured.Results Afimetoran treatment resulted ...

Vanderbilt researchers created the first high-res lipid atlas of the human kidney, mapping over 100,000 functional tissue units across 29 donors. This atlas is the most comprehensive of its kind ...

GALNT11 (Galnt11 in mice) encodes a member of the large glycosyltransferase family responsible for initiating mucin-type O-glycosylation of secreted and membrane-bound proteins (6, 7). The ortholog of ...