The results show that high blood pressure can lead to abnormalities in the podocytes, specialized cells in the renal filter, even without other pre-existing conditions such as diabetes.

Podocytes reside in a unique microenvironment where they are exposed to mechanical force and a variety of molecules that cross the filtration barrier.

Podocytes reside in a unique microenvironment where they are exposed to mechanical force and a variety of molecules that cross the filtration barrier.

To examine whether forced expression of Lamβ1 impacted podocyte phenotype and/or protected podocytes from damage in Lamb2−/− mice, we stained kidneys with antibodies to desmin, a known marker of ...

Building two-dimensional (2D) and three-dimensional (3D) micro- and nanofibril structures with designable patterns and functionalities will offer exciting prospects for numerous applications spanning ...

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PS-002 is Purespring’s lead programme developed to target the underlying cause of many kidney diseases by modulating complement activation in the kidney via precision targeting of podocytes. The ...

Many health benefits of pomegranate products have been attributed to the potent antioxidant action of their tannin components, mainly punicalagins and ellagic acid. While moving through the intestines ...