In this case, the patient initially had right pleural effusion with incomplete right lower lung atelectasis, which later developed into loculated effusion. The pleural effusion analysis showed an ...

Attempts to obliterate the pleural space go back at least as far as 1906, when Spengler 5 instilled silver nitrate in patients with spontaneous pneumothorax. Bethune 6 (1935), Medici 7 (1944) and ...

As well as the IPF candidate, the merger gave Aileron a phase-2b-ready treatment for loculated pleural effusions and a cystic fibrosis program. Finding funding for the programs remains an issue.

The following is a summary of “Predictors of lung entrapment in malignant pleural effusion,” published in the November 2024 issue of Pulmonology by Trovisco et al. Researchers conducted a ...

At age 9 years, after surgical pleurodesis and repeated selective lymphatic embolisation, the pleural effusions stabilised in size becoming chronic and loculated on medical therapy of furosemide and ...

Aileron's second product candidate, LTI-01, is a proenzyme that has completed Phase 1b and Phase 2a clinical trials for the treatment of loculated pleural effusions.

Aileron's second product candidate, LTI-01, is a proenzyme that has completed Phase 1b and Phase 2a clinical trials for the treatment of loculated pleural effusions.

The penetration ratio (PR) for each patient was obtained by dividing the AUC for pleural fluid by the AUC for the blood. Pearson’s correlation coefficient was used to assess the correlation between ...

LTI-01 is under development for the treatment of loculated pleural effusions and empyema. It is administered through intrapleural route. It is a proenzyme or zymogen and becomes activated in the ...

Pleural effusion. US National Library of Medicine. Updated Aug. 3, 2020. Accessed July 23, 2022. Porcel JM, Light RW. Diagnostic approach to pleural effusion in adults. Am Fam Physician. 2006;73 ...