Researchers from Northwest University in China developed a nano-composite hydrogel loaded with dexamethasone and kartogenin for osteoarthritis ...

A research team from Northwest University, China, has developed a breakthrough nano-composite hydrogel system to address the dual challenges of ...

Background Diversity of macrophage subsets within the joint remains unknown. The concept of macrophage polarisation into M1 inflammatory macrophages and M2 tissue-resolving macrophages, parelled by ...

An imbalance between M1 and M2 macrophage polarization is critical in osteoarthritis (OA) development. We investigated the effect of M2 macrophage-derived extracellular vesicles (M2-EVs) to ...

Macrophages are specialized immune cells, exhibiting remarkable plasticity in response to environmental stimuli. The activated macrophages broadly categorize into two different subsets, M1 and M2.

MacBook Air M2 vs MacBook Air M1: Design True to its moniker, the MacBook Air M2 is an ultra-thin and ultra-light laptop.

Macrophage M1/M2 imbalance and chronic inflammatory microenvironment have been suggested to be closely related to osteonecrosis. Here we describe direct visual evidence for the involvement of dynamic ...

Therefore, according to their expression of cell surface markers, the production of specific factors, and biological activities, Mφs are classified into the M1-like and M2-like types (3). M1 and M2 ...

Leukemia associated macrophages (LAMs), which are different from tumor-associated macrophages as well as classical M1 and M2 macrophages, are specifically activated by leukemic microenvironment. We ...

However, a particular challenge is to sustain lactate depletion. We propose that the repolarization of the tumor-supportive M2 macrophage to the tumor-suppressive M1 macrophage after the depletion of ...