In a surprising twist on cellular metabolism, scientists have uncovered a noncanonical role of the metabolic enzymePHGDH in ...

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

More information: Rachael Stewart et al, X-Ray Polarization of the Magnetar 1E 1841−045, The Astrophysical Journal Letters (2025). DOI: 10.3847/2041-8213/adbffa ...

Background: The immune microenvironment of breast cancer is richly infiltrated with macrophages, yet modulation targeting macrophage polarization has failed to achieve significant clinical efficacy.

Background: C/EBPβ is a master regulator of the mesenchymal phenotype in GBM and has an essential role in the maintenance of immunosuppressive M2 tumor-associated macrophages (TAMs). Lucicebtide is a ...

We upgraded Joe Achilles’ BMW M2 Competition with a full MSS Height Adjustable Spring (HAS) kit, giving the car a perfect mix of ride comfort and handling sharpness — without sacrificing daily ...

They are symptoms of a deeper malaise. Political polarization has reached extreme levels. Social media feeds are filled with conspiracy theories, disinformation, and personalized attacks.

More information: Buddhika Nettasinghe et al, How out-group animosity can shape partisan divisions: A model of affective polarization, PNAS Nexus (2025). DOI: 10.1093/pnasnexus/pgaf082 ...

Nothing throws America’s divisions into stark relief quite like having Donald Trump in the White House. But Mr. Trump is an effect of polarization as much as a cause. We’ve been growing apart ...

Polarization in America might be reaching a fever pitch amid a rash of escalating threats and violent attacks directed at political figures across the country. A new survey released this month by ...