In parallel, novel studies investigating immunometabolic disorders have demonstrated that agmatine can modulate macrophage polarization, shifting the balance toward an anti-inflammatory M2 phenotype.

Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

Brain macrophages serve diversified niches in the brain to maintain the organ’s homeostasis, and can play pathogenic roles in age-related brain disease. Hoping to one day replace dysfunctional ...