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This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...
β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury
Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.
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