Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most ...

In a surprising twist on cellular metabolism, scientists have uncovered a noncanonical role of the metabolic enzymePHGDH in ...

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

A review article recently published in Molecular Biomedicine by Prof. Juan Du and Dr. Xia Peng of Capital Medical University School of Stomatology ...

Additionally, these macrophages express mannose receptor, arginase 1, and dectin-1 on their surface (23, 24). The IL-4/STAT6 pathway induces ligand-dependent peroxisome proliferator-activated receptor ...

Tumor associated macrophages (TAMs) are pivotal in the tumor microenvironment, influencing angiogenesis, metastasis, and immunosuppression. This study explores macrophage polarization using a ...

Wu HM, Ni XX, Xu QY, Wang Q, Li XY, and Hua J. Regulation of lipid-induced macrophage polarization through modulating peroxisome proliferator-activated receptor-gamma activity affects hepatic lipid ...

This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...

Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

When the macrophages’ ability to consume dying cancer cells or Upd3 production was decreased, tumor growth was significantly ...