A receptor on macrophages dictated their ability to reduce inflammation after liver transplant, offering potential ...

Tumor associated macrophages (TAMs) are pivotal in the tumor microenvironment, influencing angiogenesis, metastasis, and immunosuppression. This study explores macrophage polarization using a ...

This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most ...

In a surprising twist on cellular metabolism, scientists have uncovered a noncanonical role of the metabolic enzymePHGDH in ...

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

With the development of new generation communication technology and the research of metasurface antenna technology. The new metasurface antenna has the advantages of high gain, low profile height, ...

This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

Scientists at Nagoya University in Japan studied what happens when macrophages—a type of immune cell—encounter dying cancer ...

The traditional therapeutic strategy of functionalizing repair materials with immunomodulators, drugs, and chemokines to manipulate macrophage polarization often faces challenges such as undesirable ...

"While particle recognition and phagocytosis are well understood, the epigenetic and transcriptional mechanisms regulating these signaling pathways remain incompletely defined," Cobo said.

The understanding of how macrophages regulate their response to toxic particles via two independent pathways could uncover therapeutic opportunities to quell inflammation BIRMINGHAM, Ala ...