This article examines the pathogenesis of cerebral malaria, an often fatal consequence of malaria resulting from the presence of P. falciparum-infected erythrocytes in the brain microvasculature.

Cerebral Malaria Pathogenesis Revisiting Parasite and Host Contributions Georges Emile Raymond Grau; Alister Gordon Craig Disclosures Future Microbiol. 2012;7 (2):291-302. 0 ...

This study aimed to investigate the expression of macrophage migration inhibitory factor (MIF) and CD163 in the placentas of malaria-positive and malaria-negative women and explore their potential ...

ABSTRACT: Background: Malaria has severe effects on pregnancy, and it is a primary cause of maternal and perinatal death in Sudan. This study aimed to investigate the expression of macrophage ...

Stockholm, Sweden – March 11, 2025: Modus Therapeutics Holding AB (“Modus”) announces that the Phase I clinical trial SEVUSMART, evaluating the safety and tolerability of sevuparin in children with ...

They help regulate gene activity by interacting with DNA, proteins, and other RNA molecules. Their specific roles in parasite biology and malaria pathogenesis remain poorly understood.

They help regulate gene activity by interacting with DNA, proteins, and other RNA molecules. Their specific roles in parasite biology and malaria pathogenesis remain poorly understood.

Nearly half the world’s population lives in regions where malaria is endemic, with the parasite Plasmodium falciparum accounting for approximately 95% of malaria-related deaths globally. Now, a new ...

“Severe malaria is caused by parasites binding to human EPCR through the subset of PfEMP1s that has cysteine-rich interdomain region α1 (CIDRα1) domains,” the team continued.

A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria. Science, 2024; 385 (6716) DOI: 10.1126/science.adm7966 ...

In 2022, nearly 619,000 global deaths due to malaria were caused by Plasmodium falciparum, the most virulent, prevalent, and deadly human malaria parasite. For decades, the parasite’s resistance to ...