Johns Hopkins engineers have created a new optical tool that could improve cancer imaging. Their approach, called SPECTRA, uses tiny nanoprobes that light up when they attach to aggressive cancer ...

Imaging ovarian cancer and its metastases is important for diagnosis, staging and follow-up. The authors of this Review describe functional imaging techniques that are currently used in the ...

NanoBRIGHT employs vibrational fiber photometry as a low-invasive method for label-free monitoring of the biomolecular content of arbitrarily deep regions of the mouse brain, viewed in vivo through ...

Advances in MRI, incorporating spectroscopy and perfusion techniques, and tracers unique to metastases, provide additional information on responses to treatment and enable the earlier detection of ...

Conclusions High-resolution MRI with magnetic nanoparticles allows the detection of small and otherwise undetectable lymph-node metastases in patients with prostate cancer.

Proton hydrogen 1 MR spectroscopy measures the levels of choline compounds in a lesion and identifies an active tumor. In the present study, MR spectroscopy findings were defined as positive if ...

The new tool— combining Raman spectroscopy and machine learning—introduces the Ramanome-based Metastasis Index (RMI), offering an innovative means of diagnosing and managing cancer.

They are usually sclerotic but occasionally may be lytic or mixed, particularly in high-grade tumors. CT can be used to identify bony metastases but its sensitivity is lower than bone scan and MRI ...

MR spectroscopy compared with DW-MRI and DCE-MRI at 3-tesla for the noninvasive prediction of short-term radiation response for patients with localized prostate cancer.

In the five patients with discordent results, PET scan alone was positive in three patients (metastatic lung cancer with brain metastasis-2, radiation necrosis-1). In the other two patients with ...

The team found that, unlike CT or MRI scans that can indicate the presence of a tumor but not the specific molecular signatures that can alert physicians to current or impending metastasis, SPECTRA ...