Hemifusomes are fused vesicles, or sacs of fluid, that were previously unknown to exist inside cells. They were discovered ...

Cryoelectron microscopy is a method for imaging frozen-hydrated specimens at cryogenic temperatures by electron microscopy. Specimens remain in their native state without the need for dyes or ...

Scientists have made a groundbreaking discovery in the realm of human cell biology. Through the use of cryo-electron ...

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where ...

Transmission electron microscopy is a general type of electron microscopy that generates an image of the internal structure of a thin sample using a beam of electrons to achieve much higher ...

Multiple sclerosis (MS) is a chronic inflammatory disorder that is thought to impact about 2.3 million people around the ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Researchers at Tohoku University have discovered that an oral drug called MA-5 can improve both heart and muscle problems in ...

We developed a method to improve specimen preparation for electron cryo-microscopy of membrane proteins. The method features a perforated hydrogel nanomembrane that stabilizes the thin film of aqueous ...