Microglia replacement therapy helps treat people with a rare genetic condition called ALSP, suggesting the approach could ...

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

In July 2025, Novartis Pharmaceuticals conducted a Phase III multi-center, single dose (1.2 x 1014 vector genomes), ...

Scientists with the NIH-backed SMaHT Network are mapping every DNA mutation in the human body, creating a groundbreaking ...

According to the study, a single genetic mutation in the NOVA1 gene, unique to modern humans, may have impacted the development of brain pathways essential for vocal behavior. By genetically modifying ...

A single mutation in the surface protein of the highly pathogenic avian influenza (HPAI) H5N1 influenza virus could allow for easier human transmission.

The authors wrote that the pathogen, which first popped up in North America in 2021, is just a “single mutation ” away from being able to infect humans with the same efficacy it can currently ...

A new study has raised alarm bells about the potential for the H5N1 bird flu virus to evolve into a strain sparking a human pandemic. A single mutation in the virus currently ravaging dairy farms ...

Single bird flu mutation could let it latch easily to human cells, study finds The potential mutation would allow the virus to hitch itself to a protein on the surface of our cells, known as the ...

Although more than 50 humans have been infected by H5N1, many of these cases involve dairy workers who were likely sprayed in the eyes and nose with milk from infected cows. Researchers postulate ...

Lee went on to elucidate the molecular mechanisms underlying this effect, identifying the following: naturally-occurring myostatin mutations in cattle (with Alexandra McPherron and concurrently with ...