Microglia replacement therapy helps treat people with a rare genetic condition called ALSP, suggesting the approach could ...

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

In July 2025, Novartis Pharmaceuticals conducted a Phase III multi-center, single dose (1.2 x 1014 vector genomes), ...

Scientists with the NIH-backed SMaHT Network are mapping every DNA mutation in the human body, creating a groundbreaking ...

The rate-limiting proton transfer (PT) event in the site-specific mutant N67L of human carbonic anhydrase II (HCA II) has been examined by kinetic, X-ray, and simulation approaches. The X-ray ...

LSO-037 STING/TMEM173 mutation in systemic lupus erythematosus: from animal model to intrinsic human genetics Author affiliations • Pichpisith Vejvisithsakul 1 , Satima Wanachate 1 , Pintip ...

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The ...

Discover how snowflake yeast defies expectations, growing exponentially due to physical processes, challenging traditional views on evolution.

A new study that examined animal species with a cancer resistance gene could help human cancer research.

Viruses closely related to the deadly MERS coronavirus are lurking in bats and one group, known as HKU5, may be just one mutation away from making the jump to humans. A new study reveals how these ...