BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

Quantitative measurements of intra-Golgi transport kinetics of diverse secretory cargos challenge the classic cisternal progression model and support the stable compartment model of the Golgi.

Fibroblasts reprogrammed into AT2-like lung cells in just 7–10 days, offering a faster, safer alternative to stem cell ...

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without ...

Alzheimer's disease (AD) is a debilitating neurodegenerative condition that affects a significant proportion of older people worldwide. Synapses are ...

Animals and insects inside your home aren’t just a nuisance; they’re potential trouble, spreading pathogens and harming property. When can you manage the situation on your own and when do you need ...

To study the genetic causes of autism spectrum disorder, a Kobe University research team has created a bank of 63 mouse embryonic stem cell lines containing the mutations most strongly associated ...

From a cubic millimeter of brain tissue, scientists have constructed a precise, 3D map of the activity in a mouse’s brain, detailing 84,000 neurons and more than 500 million synapses.

For the first time, the smallest control system of vision in mammals has been mapped—a discovery that opens entirely new ...

Researchers have created the largest and most detailed wiring diagram of a mammalian brain to date, by mapping cells in a cubic millimetre of a mouse’s brain tissue. In a landmark achievement ...

Scientists achieved “a milestone” by charting the activity and structure of 200,000 cells in a mouse brain and their 523 million connections.

imageimageThe respective contribution of tumour suppressor p53-activated cellular response pathways to prevention of tumour development remains debated. This resource introduces three novel mouse ...