Objective To conduct a systematic review investigating the normal age-related changes in lung function in adults without known lung disease. Design Systematic review. Data sources MEDLINE, Embase and ...

Methods/Design: This is to be a randomized, multicentre, open-label clinical trial. A total of 444 smokers over 40 years of age will be recruited by 39 general practitioners from 22 health centers ...

Discussion: Performing a spirometry test and providing information on pulmonary function may increase awareness of the effect of smoking among smokers who are asymptomatic or have few symptoms and ...

A sample of 444 people will be recruited. The sample size calculation was based on assuming a level of significance of 5%, a quit rate after brief anti-smoking intervention only (control group) of ...

Spirometry measurements included forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and the FEV1/FVC ratio. Spirometry outcomes were categorized into three groups based on ...

This high negative predictive value for spirometry (91%) means that a negative test (normal spirometry) probably indicates absence of asthma. It is worthy bearing in mind that predictive value ...

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This is the most severe stage of COPD. Your FEV1 is less than 30% of normal predicted values or less than 50% with chronic respiratory failure. At this stage, your quality of life is greatly impaired.

Significant increases occurred for FEV1 and FVC, with a reduced but statistically significant decrease in FEV1/FVC. The use of the GLI Global equations resulted in a change in the spirometry pattern ...

For example, lower FVC values indicate restricted breathing and lower FEV1 readings indicate bronchial obstruction. In healthy people, the FEV1/FVC ratio is 70 to 80 percent. If values are lower than ...

Stage 1: This is when your FEV1 is equal to or greater than the predicted normal and your FEV1/FVC ratio is less than 70%. Your symptoms are likely to be very mild or even unnoticeable. Stage 2 ...

Normal ageing is strongly associated with lower FVC and reduced FVC may not actively identify true pulmonary restriction in the elderly. 32 Although low FVC may identify restrictive lung patterns in ...