"These cases are broadly referred to with the term 'body-first PD.' To identify the organs where α-synuclein pathology begins, we stained the peripheral organs and found that the kidneys were ...

Tau protein is essential for microtubule stability and neuronal function. The protein’s disfunction is linked to several ...

Damaged mitochondrial DNA (mtDNA) initiates and spreads Parkinson's disease (PD) pathology, potentially opening new avenues for early diagnosis, disease monitoring, and drug development.. While ...

It separates, with a stunning 90 percent specificity, those who have evidence of PD pathology in their cells from those who do not. It does so even before the emergence of symptoms, ...

Drs. Fatemeh Ardeshir-Larijani and Mohamed Abazeed discuss a validated AI model that can predict how patients with advanced ...

Overall, 36 percent of PD-associated species had greater than twofold change in abundance, reflecting a 100 percent to 750 percent increase or decrease in PD versus the healthy control group. “This ...

UB-312 is the first Parkinson's candidate to reduce pathology as measured by a seed amplification assay, and suggest clinical improvement on motor experiences of daily living. Data demonstrates ...

NORTHFIELD, Ill., April 16, 2024--The College of American Pathologists (CAP) in collaboration with the International Association for the Study of Lung Cancer (IASLC), Pulmonary Pathology Society ...

Deposition of α-synuclein in the kidneys of PD patients. Credit: Yuan et al. Nature Neuroscience (2025). DOI: 10.1038/s41593-024-01866-2.