For patients with psoriasis and Type 2 diabetes, the risk of developing chronic kidney disease (CKD) continued to rise ...

AD and psoriasis were once thought to be opposites in terms of immune response, with AD linked to a Th2-dominant pathway and ...

Tumor necrosis factor (TNF) inhibitor therapy was effective in reducing the likelihood that psoriasis would progress to psoriatic arthritis (PsA), a retrospective study indicated. Among ...

Psoriasis can occur near the eyes, causing redness, itching, dryness, and flaking skin. Once it’s correctly diagnosed, you can often manage it with topical treatments.

The digital annular pulleys (DAP) of the hand are specialised fibrous structures that stabilise the flexor tendons. We recently demonstrated that the insertions of the DAP are anatomical entheses, ...

Tumor necrosis factor-alpha (TNF-α) and interleukin (IL) inhibitors are biologic agents that selectively inhibit cytokines involved in the pathogenesis of psoriasis (Table). 11,13 Biologics have ...

Overall, the study showed that the hormonal peptide hepcidin, which is involved in the systemic regulation of iron levels in the body, plays a major role in the pathogenesis of psoriasis by ...

Scientists believe the hormone hepcidin, when produced in the skin, may be the root cause of psoriasis – a chronic and sometimes debilitating skin disease that affects 2-3% of the global ...

Pathogenesis of Psoriasis For most of its history, psoriasis has been thought of as a disease localized to the skin and primarily being driven by abnormalities in keratinocytes.

The management of psoriasis revolves around injectable biologics that target T helper 17 cells-derived proinflammatory cytokines responsible for the pathogenesis of the disease. IL-23 inhibitors ...

Both companies have found answers in each other. Oruka and ARCA are pursuing a reverse merger intended to create a $300 million-plus combined company focused on treating plaque psoriasis and other ...

Many people with psoriasis experience flare-ups, or periods of time when symptoms become more active. These flares can last anywhere from weeks to months, and there is a range of triggers that can ...