Individualized ocular characteristics should be considered before starting GLP-1 RA therapies for weight loss and diabetes ...

Researchers have illustrated how inflammatory and systemic factors contribute to myopenia, sarcopenia, and cachexia in ...

When ocrelizumab became the first FDA-approved treatment for early forms of multiple sclerosis (MS) in 2017, it offered ...

Autoimmune diseases, especially in women, are associated with nearly a twofold increased risk for affective disorders, new ...

IL-6 is an important proinflammatory cytokine that is integral to the pathogenesis of RA and other autoimmune diseases. The hypothesis that targeting and inhibiting IL-6R with tocilizumab can ...

Taken together, these results strongly suggest that the intracellular environment and immune cell function play an important role in the pathogenesis of polycystic ovaries and rheumatoid arthritis.

In a rodent model of type 2 diabetes (T2D), icovamenib in combination with low-dose semaglutide promoted enhanced glycemic control and b ...

Rheumatoid arthritis (RA) is characterised by a chronic inflammatory condition of the joints, but the comorbidities of RA predominantly contribute to the reduced lifespan associated with this disease.

Objective This study aimed to examine rheumatoid arthritis (RA) risk associated with hormonal and reproductive factors in women from the large cohort of the UK Biobank.Methods Data on hormonal and ...

Recently, Hollander and coworkers have identified HIF-1α in RA synovial tissue, predominantly in macrophages. 43 Moreover, Cramer and colleagues showed that when the HIF-1α gene was deleted in mice, ...

Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects individuals across all ages and genders.

Carpal tunnel syndrome may serve as an early, underrecognized clinical feature of RA, especially among seronegative patients.